Technologies
Life Science and biocomputing
Triacle Biocomputing offers a considerable expertise in particular areas of biocomputing, as exemplified in these scientific publications in peer reviewed well established journals.
Software development
The development of life science software is based upon sound object-oriented analysis and design. The firm employs, among other, C++, Java and XML. Life science application software can be either developed for the Unix/Linux or the Windows environment, while expertise also exist to build a web application with XSLT, Cocoon and, for instance, Xindice.
Web applications and Website design
Triacle Biocomputing designs websites with web standards, that is HTML, XHTML and XML for structure, CSS for presentation, and ECMAScript and DOM for behaviour. A great deal of effort is spent to ensure that a website or web application is accessible to every device (e.g. Palm Pilots, web-enabled cell phones, screen readers, text browsers, alternative browsers and devices).
Recent publications
S. Donnini, A. Villa, G. Groenhof, A. E. Mark, R.W. Wierenga, A.H. Juffer, Inclusion of ionization states of ligand in affinity calculations. Proteins 76, 138 - 150, 2009.
A.H. Juffer, U. Marina, O. Niemitalo, J. Koivukangas, Computer modeling of brain tumor growth (review). Mini Rev. Med. Chem. 8, 1494-506, 2008.
S. Sharma, A. Rauk, A.H. Juffer, A DFT Study of Phosphohistidine Enzyme Intermediateon in Prostatic Acid Phosphatase. J. Am. Chem. Soc, 130, 9708 - 9716, 2008.
W Xin and A.H.Juffer, A boundary element formulation of protein electrostatics with explicit ions. J Comput Phys, 223, 416 - 435, 2007.
S. Donnini, G Groenhof, R.K. Wierenga, A.H. Juffer, The planar conformation of a strained proline ring: a QM/MM study, Proteins, 64, 700-710, 2006
O. Niemitalo, A. Neubauer, U. Liebal, J. Myllyharju, A.H. Juffer and P Neubauer, Modelling of translation of human protein disulfide isomerase in Escherichia coli. A case study of gene optimisation, J. Biotechnology, 12, 11-24, 2005.
